Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids.
Publication
, Journal Article
Strittmatter, WJ; Hirata, F; Axelrod, J
Published in: Adv Cyclic Nucleotide Res
1981
Stimulation of the beta-adrenergic receptor increases the enzymatic methylation of membrane phospholipids. Increased synthesis of phosphatidyl-N-monomethylethanolamine by methyltransferase I increases fluidity and enhances the ability of the beta-adrenergic receptor to couple with adenylate cyclase. The number of beta-adrenergic receptors can be regulated by the rate of synthesis and of degradation of phosphatidylcholine formed by transmethylation.
Duke Scholars
Published In
Adv Cyclic Nucleotide Res
ISSN
0084-5930
Publication Date
1981
Volume
14
Start / End Page
83 / 91
Location
United States
Related Subject Headings
- Reticulocytes
- Receptors, Adrenergic, beta
- Receptors, Adrenergic
- Phospholipids
- Methyltransferases
- Methylation
- Membrane Lipids
- Membrane Fluidity
- Lipid Bilayers
- Isoproterenol
Citation
APA
Chicago
ICMJE
MLA
NLM
Strittmatter, W. J., Hirata, F., & Axelrod, J. (1981). Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Adv Cyclic Nucleotide Res, 14, 83–91.
Strittmatter, W. J., F. Hirata, and J. Axelrod. “Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids.” Adv Cyclic Nucleotide Res 14 (1981): 83–91.
Strittmatter WJ, Hirata F, Axelrod J. Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Adv Cyclic Nucleotide Res. 1981;14:83–91.
Strittmatter, W. J., et al. “Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids.” Adv Cyclic Nucleotide Res, vol. 14, 1981, pp. 83–91.
Strittmatter WJ, Hirata F, Axelrod J. Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Adv Cyclic Nucleotide Res. 1981;14:83–91.
Published In
Adv Cyclic Nucleotide Res
ISSN
0084-5930
Publication Date
1981
Volume
14
Start / End Page
83 / 91
Location
United States
Related Subject Headings
- Reticulocytes
- Receptors, Adrenergic, beta
- Receptors, Adrenergic
- Phospholipids
- Methyltransferases
- Methylation
- Membrane Lipids
- Membrane Fluidity
- Lipid Bilayers
- Isoproterenol