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Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids.

Publication ,  Journal Article
Strittmatter, WJ; Hirata, F; Axelrod, J
Published in: Adv Cyclic Nucleotide Res
1981

Stimulation of the beta-adrenergic receptor increases the enzymatic methylation of membrane phospholipids. Increased synthesis of phosphatidyl-N-monomethylethanolamine by methyltransferase I increases fluidity and enhances the ability of the beta-adrenergic receptor to couple with adenylate cyclase. The number of beta-adrenergic receptors can be regulated by the rate of synthesis and of degradation of phosphatidylcholine formed by transmethylation.

Duke Scholars

Published In

Adv Cyclic Nucleotide Res

ISSN

0084-5930

Publication Date

1981

Volume

14

Start / End Page

83 / 91

Location

United States

Related Subject Headings

  • Reticulocytes
  • Receptors, Adrenergic, beta
  • Receptors, Adrenergic
  • Phospholipids
  • Methyltransferases
  • Methylation
  • Membrane Lipids
  • Membrane Fluidity
  • Lipid Bilayers
  • Isoproterenol
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Strittmatter, W. J., Hirata, F., & Axelrod, J. (1981). Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Adv Cyclic Nucleotide Res, 14, 83–91.
Strittmatter, W. J., F. Hirata, and J. Axelrod. “Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids.Adv Cyclic Nucleotide Res 14 (1981): 83–91.
Strittmatter WJ, Hirata F, Axelrod J. Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Adv Cyclic Nucleotide Res. 1981;14:83–91.
Strittmatter, W. J., et al. “Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids.Adv Cyclic Nucleotide Res, vol. 14, 1981, pp. 83–91.
Strittmatter WJ, Hirata F, Axelrod J. Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Adv Cyclic Nucleotide Res. 1981;14:83–91.

Published In

Adv Cyclic Nucleotide Res

ISSN

0084-5930

Publication Date

1981

Volume

14

Start / End Page

83 / 91

Location

United States

Related Subject Headings

  • Reticulocytes
  • Receptors, Adrenergic, beta
  • Receptors, Adrenergic
  • Phospholipids
  • Methyltransferases
  • Methylation
  • Membrane Lipids
  • Membrane Fluidity
  • Lipid Bilayers
  • Isoproterenol