Oral manifestations of chronic graft-v-host disease.

Journal Article (Journal Article)

Sixty patients were studied 180 to 500 days after allogeneic marrow transplantation to determine if late oral abnormalities were associated with the presence of chronic graft-v-host disease (GVHD). Lip and intraoral mucosal surfaces were evaluated for color, keratinization, atrophy, and erythema. Subjective complaints of oral pain and xerostomia were also recorded. Abnormalities were scored on a scale of 0 to 3 and tested for association with GVHD by chi 2 test. Oral manifestations most strongly associated with chronic GVHD included atrophy and erythema or lichenoid lesions of the buccal and labial mucosa and oral pain. Oral manifestations resembled several naturally occurring autoimmune disorders. Recognition of these changes can aid in the clinical diagnosis and assessment of established chronic GVHD.

Full Text

Duke Authors

Cited Authors

  • Schubert, MM; Sullivan, KM; Morton, TH; Izutsu, KT; Peterson, DE; Flournoy, N; Truelove, EL; Sale, GE; Buckner, CD; Storb, R

Published Date

  • August 1984

Published In

Volume / Issue

  • 144 / 8

Start / End Page

  • 1591 - 1595

PubMed ID

  • 6380439

International Standard Serial Number (ISSN)

  • 0003-9926


  • eng

Conference Location

  • United States