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Oral manifestations of chronic graft-v-host disease.

Publication ,  Journal Article
Schubert, MM; Sullivan, KM; Morton, TH; Izutsu, KT; Peterson, DE; Flournoy, N; Truelove, EL; Sale, GE; Buckner, CD; Storb, R
Published in: Arch Intern Med
August 1984

Sixty patients were studied 180 to 500 days after allogeneic marrow transplantation to determine if late oral abnormalities were associated with the presence of chronic graft-v-host disease (GVHD). Lip and intraoral mucosal surfaces were evaluated for color, keratinization, atrophy, and erythema. Subjective complaints of oral pain and xerostomia were also recorded. Abnormalities were scored on a scale of 0 to 3 and tested for association with GVHD by chi 2 test. Oral manifestations most strongly associated with chronic GVHD included atrophy and erythema or lichenoid lesions of the buccal and labial mucosa and oral pain. Oral manifestations resembled several naturally occurring autoimmune disorders. Recognition of these changes can aid in the clinical diagnosis and assessment of established chronic GVHD.

Duke Scholars

Published In

Arch Intern Med

ISSN

0003-9926

Publication Date

August 1984

Volume

144

Issue

8

Start / End Page

1591 / 1595

Location

United States

Related Subject Headings

  • Xerostomia
  • Time Factors
  • Stomatitis
  • Prospective Studies
  • Pain
  • Mouth Mucosa
  • Mouth Diseases
  • Male
  • Lichen Planus
  • Leukemia
 

Citation

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Schubert, M. M., Sullivan, K. M., Morton, T. H., Izutsu, K. T., Peterson, D. E., Flournoy, N., … Storb, R. (1984). Oral manifestations of chronic graft-v-host disease. Arch Intern Med, 144(8), 1591–1595.
Schubert, M. M., K. M. Sullivan, T. H. Morton, K. T. Izutsu, D. E. Peterson, N. Flournoy, E. L. Truelove, G. E. Sale, C. D. Buckner, and R. Storb. “Oral manifestations of chronic graft-v-host disease.Arch Intern Med 144, no. 8 (August 1984): 1591–95.
Schubert MM, Sullivan KM, Morton TH, Izutsu KT, Peterson DE, Flournoy N, et al. Oral manifestations of chronic graft-v-host disease. Arch Intern Med. 1984 Aug;144(8):1591–5.
Schubert, M. M., et al. “Oral manifestations of chronic graft-v-host disease.Arch Intern Med, vol. 144, no. 8, Aug. 1984, pp. 1591–95.
Schubert MM, Sullivan KM, Morton TH, Izutsu KT, Peterson DE, Flournoy N, Truelove EL, Sale GE, Buckner CD, Storb R. Oral manifestations of chronic graft-v-host disease. Arch Intern Med. 1984 Aug;144(8):1591–1595.

Published In

Arch Intern Med

ISSN

0003-9926

Publication Date

August 1984

Volume

144

Issue

8

Start / End Page

1591 / 1595

Location

United States

Related Subject Headings

  • Xerostomia
  • Time Factors
  • Stomatitis
  • Prospective Studies
  • Pain
  • Mouth Mucosa
  • Mouth Diseases
  • Male
  • Lichen Planus
  • Leukemia