Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies.
Publication
, Journal Article
Swartzwelder, HS; Johnson, CT; Cooley, BC; Howell, WE; Dyer, RS
Published in: Neurobehav Toxicol
1979
The hippocampal afterdischarge (AD) has been suggested as an index of toxicant-induced CNS change [1]. The present experiments report raised AD thresholds, decreased AD durations, shorter post-stimulation latencies to AD onset, decreased numbers of AD spike complexes and increased numbers of spikes/complex following alcohol administration. Results are discussed in light of single-unit data concerning alcohol effects upon hippocampal cells, and the biphasic effects of alcohol upon behavior.
Duke Scholars
Published In
Neurobehav Toxicol
ISSN
0191-3581
Publication Date
1979
Volume
1
Issue
4
Start / End Page
253 / 258
Location
United States
Related Subject Headings
- Regression Analysis
- Rats
- Male
- Hippocampus
- Ethanol
- Electroencephalography
- Electric Stimulation
- Dose-Response Relationship, Drug
- Differential Threshold
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Swartzwelder, H. S., Johnson, C. T., Cooley, B. C., Howell, W. E., & Dyer, R. S. (1979). Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies. Neurobehav Toxicol, 1(4), 253–258.
Swartzwelder, H. S., C. T. Johnson, B. C. Cooley, W. E. Howell, and R. S. Dyer. “Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies.” Neurobehav Toxicol 1, no. 4 (1979): 253–58.
Swartzwelder HS, Johnson CT, Cooley BC, Howell WE, Dyer RS. Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies. Neurobehav Toxicol. 1979;1(4):253–8.
Swartzwelder, H. S., et al. “Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies.” Neurobehav Toxicol, vol. 1, no. 4, 1979, pp. 253–58.
Swartzwelder HS, Johnson CT, Cooley BC, Howell WE, Dyer RS. Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies. Neurobehav Toxicol. 1979;1(4):253–258.
Published In
Neurobehav Toxicol
ISSN
0191-3581
Publication Date
1979
Volume
1
Issue
4
Start / End Page
253 / 258
Location
United States
Related Subject Headings
- Regression Analysis
- Rats
- Male
- Hippocampus
- Ethanol
- Electroencephalography
- Electric Stimulation
- Dose-Response Relationship, Drug
- Differential Threshold
- Animals