Metal accumulation and transport in the ovary of the lizard Podarcis sicula


Journal Article

The molecular characterisation of a CTR protein is reported in the ovary of the lizard Podarcis sicula; this protein proves to be homologous with the mammalian high affinity copper transporter CTRL Gene expression assessed by Northern blot hybridisation of RNA from growing ovarian follicles and eggs demonstrated that the transcript accumulated during the oocyte growth and reached the highest levels in ovulated eggs. Analysis of the copper content paralleled the profile of CTR1 mRNA, with a rapid increase of the metal concentration during oocyte maturation. These data suggest that the P. sicula CTR1 protein may function in the uptake and storage of the copper to be used during embryonic development.

Full Text

Duke Authors

Cited Authors

  • Riggio, M; Scudiero, R; Lee, J; Thiele, DJ; Parisi, E; Filosa, S

Published Date

  • December 1, 2004

Published In

Volume / Issue

  • 71 / SUPPL.2

Start / End Page

  • 59 - 62

Electronic International Standard Serial Number (EISSN)

  • 1748-5851

International Standard Serial Number (ISSN)

  • 1125-0003

Digital Object Identifier (DOI)

  • 10.1080/11250000409356607

Citation Source

  • Scopus