Reproduction life history and hip fractures.

Journal Article (Journal Article)


The present study assesses the association between reproduction and hip fractures.


We used two surveys on elderly Danish twins of both sexes and the Danish National Register of Patients. In a cross-sectional study of 2045 twins aged 75-98 years in 1995, we studied the association between different aspects of reproduction and hip fractures leading to hospitalization between 1977 and 1994. In a prospective study, 3057 twins aged 66-99 years in 1977 were followed for a total of 29,112 years, and the association between number of children and incidence of hip fractures was investigated.


In the cross-sectional study, as well as the prospective study, we found, for both sexes, that having no children was associated with a higher risk of hip fracture compared to having at least one child. When excluding persons without children, we found no effect of number of birth events/children. In the cross-sectional study, we found no effect of birth interval length or age at first birth. For women, we found an effect of age at last birth.


No "cost-of-reproduction" in terms of hip fractures was observed. On the contrary, we found that having one or more children was associated with a lower risk of hip fracture.

Full Text

Duke Authors

Cited Authors

  • Petersen, HC; Jeune, B; Vaupel, JW; Christensen, K

Published Date

  • May 2002

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 257 - 263

PubMed ID

  • 11988414

Electronic International Standard Serial Number (EISSN)

  • 1873-2585

International Standard Serial Number (ISSN)

  • 1047-2797

Digital Object Identifier (DOI)

  • 10.1016/s1047-2797(01)00275-7


  • eng