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Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis.

Publication ,  Journal Article
Vo-Dinh, T; Panjehpour, M; Overholt, BF
Published in: Annals of the New York Academy of Sciences
February 1998

A method using laser-induced fluorescence (LIF) for in vivo cancer diagnosis of the esophagus is described. Autofluorescence of normal and malignant tissues was measured directly using a fiberoptic probe inserted through an endoscope. The measurements were performed in vivo during routine endoscopy. Measurement of the fluorescence signal from the tissue was performed using laser excitation at 410 nm. The methodology was applied to differentiate normal and malignant tumors of the esophagus. The results of this LIF approach were compared with histopathology results of the biopsy samples and indicated excellent agreement in the classification of normal and malignant tumors for the samples investigated. The LIF procedure could lead to the development of a rapid and cost-effective technique for cancer diagnosis.

Duke Scholars

Published In

Annals of the New York Academy of Sciences

DOI

EISSN

1749-6632

ISSN

0077-8923

Publication Date

February 1998

Volume

838

Start / End Page

116 / 122

Related Subject Headings

  • Lasers
  • Humans
  • General Science & Technology
  • Fluorescence
  • Esophageal Neoplasms
  • Cost-Benefit Analysis
  • Biopsy
  • Barrett Esophagus
 

Citation

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MLA
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Vo-Dinh, T., Panjehpour, M., & Overholt, B. F. (1998). Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis. Annals of the New York Academy of Sciences, 838, 116–122. https://doi.org/10.1111/j.1749-6632.1998.tb08192.x
Vo-Dinh, T., M. Panjehpour, and B. F. Overholt. “Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis.Annals of the New York Academy of Sciences 838 (February 1998): 116–22. https://doi.org/10.1111/j.1749-6632.1998.tb08192.x.
Vo-Dinh T, Panjehpour M, Overholt BF. Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis. Annals of the New York Academy of Sciences. 1998 Feb;838:116–22.
Vo-Dinh, T., et al. “Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis.Annals of the New York Academy of Sciences, vol. 838, Feb. 1998, pp. 116–22. Epmc, doi:10.1111/j.1749-6632.1998.tb08192.x.
Vo-Dinh T, Panjehpour M, Overholt BF. Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis. Annals of the New York Academy of Sciences. 1998 Feb;838:116–122.
Journal cover image

Published In

Annals of the New York Academy of Sciences

DOI

EISSN

1749-6632

ISSN

0077-8923

Publication Date

February 1998

Volume

838

Start / End Page

116 / 122

Related Subject Headings

  • Lasers
  • Humans
  • General Science & Technology
  • Fluorescence
  • Esophageal Neoplasms
  • Cost-Benefit Analysis
  • Biopsy
  • Barrett Esophagus