Electrocardiographic ST-segment changes during acute myocardial ischemia.


Journal Article (Review)

The recognition and management of patients with acute coronary syndromes has relied to a large extent on the standard 12-lead electrocardiogram (ECG) for assessing ST-segment changes associated with ischemia. The purpose of this review is to show both the capabilities and the limitations of the 12-lead ECG in recognizing ischemia, and to seek alternative electrocardiographic leads, optimized for detection of ischemia originating in different regions of the ventricular myocardium. Three such leads are proposed-based on the results obtained by electrocardiographic body-surface mapping performed during ischemia induced by balloon-inflation coronary angioplasty. A survey of recent clinical studies shows that the electrocardiographic manifestations of acute myocardial ischemia observed during coronary angioplasty are in agreement with the ST-segment measurements in admission ECGs of patients with acute myocardial infarction.

Full Text

Cited Authors

  • Horácek, BM; Wagner, GS

Published Date

  • September 2002

Published In

Volume / Issue

  • 6 / 3

Start / End Page

  • 196 - 203

PubMed ID

  • 12114838

Pubmed Central ID

  • 12114838

International Standard Serial Number (ISSN)

  • 1385-2264

Digital Object Identifier (DOI)

  • 10.1023/a:1016352205286


  • eng