Electrocardiographic changes during prolonged coronary artery occlusion in man: comparison of standard and high-frequency recordings.


Journal Article

Detection of acute myocardial ischaemia using electrocardiographic methods is generally based on assessment of the ST segments in the standard 12-lead electrocardiogram (ECG). Several studies have also shown changes in high-frequency QRS components during acute ischaemia. The purpose of the present study was to determine the changes in high-frequency QRS components during prolonged percutaneous transluminal coronary angioplasty (PTCA) and to compare these changes with ST-segment deviations in the standard 12-lead ECG. The study population consisted of 19 patients receiving prolonged PTCA. Standard and high-resolution signal-averaged ECGs were recorded before and during balloon inflation. The high-resolution recordings were performed using bipolar X, Y and Z leads. The QRS complexes in the high-resolution signal-averaged ECGs were analysed within a bandwidth of 150-250 Hz. During inflation, significant reductions in high-frequency QRS components were observed (12-72%). Changes in the high-frequency QRS components were seen in four of the patients without ST-segments deviation in the standard ECG. The correlation between the ST-segment deviation and the reduction in high-frequency QRS components was weak (r = 0.27). Acute coronary artery occlusion produces changes in high-frequency QRS components, even in the absence of ST-segment deviation in the standard ECG. Further studies need to be carried out to evaluate whether analysis of high-frequency QRS components could provide a method for detecting myocardial ischaemia and give additional information to that available in the ST segment in the standard ECG.

Full Text

Cited Authors

  • Pettersson, J; Lander, P; Pahlm, O; Sörnmo, L; Warren, SG; Wagner, GS

Published Date

  • May 1998

Published In

Volume / Issue

  • 18 / 3

Start / End Page

  • 179 - 186

PubMed ID

  • 9649905

Pubmed Central ID

  • 9649905

Electronic International Standard Serial Number (EISSN)

  • 1365-2281

International Standard Serial Number (ISSN)

  • 0144-5979

Digital Object Identifier (DOI)

  • 10.1046/j.1365-2281.1998.00091.x


  • eng