Testicular seminoma revisited: Time for a multimodal therapeutic approach

Journal Article (Journal Article)

The development of effective chemotherapy regimens for germ-cell carcinoma has mandated a reassessment of the management of testicular seminoma, since patients with advanced seminoma respond poorly to radiotherapy. Although traditional radiotherapy regimens are effective against clinical Stages A and B1 disease, cisplatin-based chemotherapy may be preferable for Stages B2 and C disease. Alternatively, vinblastine, actinomycin D (dactinomycin), and cyclophosphamide may be used in conjunction with consolidation radiotherapy, reserving cisplatin and bleomycin for salvage treatment. In stage D disease, cisplatin-based chemotherapy may be advisable. The use of CT scans to improve the accuracy of clinical staging is suggested. © 1984 Springer-Verlag.

Full Text

Duke Authors

Cited Authors

  • Walther, PJ; Paulson, DF

Published Date

  • March 1, 1984

Published In

Volume / Issue

  • 2 / 1

Start / End Page

  • 68 - 72

Electronic International Standard Serial Number (EISSN)

  • 1433-8726

International Standard Serial Number (ISSN)

  • 0724-4983

Digital Object Identifier (DOI)

  • 10.1007/BF00326938

Citation Source

  • Scopus