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Intraoperative radiation therapy.

Publication ,  Journal Article
Willett, CG
Published in: Int J Clin Oncol
October 2001

The modern use of intraoperative radiation therapy (IORT) was initiated by the studies of Abe and colleagues at the University of Kyoto. This work stimulated significant laboratory and clinical investigation into the use of IORT throughout Japan, Europe, and the United States. Because of this experience, single high doses of irradiation can be safely delivered to a tumor volume in appropriate clinical situations. Most importantly, this high dose of additional radiation treatment yields improved local control of selected tumors. Treatment programs of external beam radiation therapy, surgical resection, and IORT for patients with locally advanced primary and recurrent rectal carcinoma and retroperitoneal sarcoma have yielded excellent local control and higher survival rates. The future of IORT will be in the successful integration of this therapy into multimodality treatment programs of chemotherapy, external beam irradiation, and surgery for locally advanced malignancies.

Duke Scholars

Published In

Int J Clin Oncol

DOI

ISSN

1341-9625

Publication Date

October 2001

Volume

6

Issue

5

Start / End Page

209 / 214

Location

Japan

Related Subject Headings

  • Survival Rate
  • Sarcoma
  • Retroperitoneal Neoplasms
  • Rectal Neoplasms
  • Radiotherapy, High-Energy
  • Radiation Tolerance
  • Oncology & Carcinogenesis
  • Male
  • Intraoperative Period
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Willett, C. G. (2001). Intraoperative radiation therapy. Int J Clin Oncol, 6(5), 209–214. https://doi.org/10.1007/pl00012107
Willett, C. G. “Intraoperative radiation therapy.Int J Clin Oncol 6, no. 5 (October 2001): 209–14. https://doi.org/10.1007/pl00012107.
Willett CG. Intraoperative radiation therapy. Int J Clin Oncol. 2001 Oct;6(5):209–14.
Willett, C. G. “Intraoperative radiation therapy.Int J Clin Oncol, vol. 6, no. 5, Oct. 2001, pp. 209–14. Pubmed, doi:10.1007/pl00012107.
Willett CG. Intraoperative radiation therapy. Int J Clin Oncol. 2001 Oct;6(5):209–214.
Journal cover image

Published In

Int J Clin Oncol

DOI

ISSN

1341-9625

Publication Date

October 2001

Volume

6

Issue

5

Start / End Page

209 / 214

Location

Japan

Related Subject Headings

  • Survival Rate
  • Sarcoma
  • Retroperitoneal Neoplasms
  • Rectal Neoplasms
  • Radiotherapy, High-Energy
  • Radiation Tolerance
  • Oncology & Carcinogenesis
  • Male
  • Intraoperative Period
  • Humans