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Radiation therapy in the management of rectal cancer.

Publication ,  Journal Article
Kachnic, LA; Willett, CG
Published in: Curr Opin Oncol
July 2001

Substantial advances have been made in the adjuvant management of patients with resectable rectal cancer. Increasing interest in patient quality of life has promoted the use of radiation therapy to enhance sphincter-preserving surgical approaches as an alternative to the standard abdominoperineal resection. Because of the suggestion of enhanced sphincter preservation with preoperative therapy and the potential advantage of decreased acute morbidity, randomized trials comparing preoperative and postoperative adjuvant combined modality therapy are ongoing. Recent progress in adjuvant postoperative treatment regimens relates to the integration of systemic therapy to radiation, and redefining the techniques for both modalities. The incorporation of improved radiation planning may reduce treatment-related bowel toxicity. The integration of novel chemotherapeutic agents in the adjuvant therapy of rectal cancer remains an active area of investigation.

Duke Scholars

Published In

Curr Opin Oncol

DOI

ISSN

1040-8746

Publication Date

July 2001

Volume

13

Issue

4

Start / End Page

300 / 306

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Rate
  • Rectal Neoplasms
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Humans
  • Combined Modality Therapy
  • Clinical Trials as Topic
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
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ICMJE
MLA
NLM
Kachnic, L. A., & Willett, C. G. (2001). Radiation therapy in the management of rectal cancer. Curr Opin Oncol, 13(4), 300–306. https://doi.org/10.1097/00001622-200107000-00014
Kachnic, L. A., and C. G. Willett. “Radiation therapy in the management of rectal cancer.Curr Opin Oncol 13, no. 4 (July 2001): 300–306. https://doi.org/10.1097/00001622-200107000-00014.
Kachnic LA, Willett CG. Radiation therapy in the management of rectal cancer. Curr Opin Oncol. 2001 Jul;13(4):300–6.
Kachnic, L. A., and C. G. Willett. “Radiation therapy in the management of rectal cancer.Curr Opin Oncol, vol. 13, no. 4, July 2001, pp. 300–06. Pubmed, doi:10.1097/00001622-200107000-00014.
Kachnic LA, Willett CG. Radiation therapy in the management of rectal cancer. Curr Opin Oncol. 2001 Jul;13(4):300–306.

Published In

Curr Opin Oncol

DOI

ISSN

1040-8746

Publication Date

July 2001

Volume

13

Issue

4

Start / End Page

300 / 306

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Rate
  • Rectal Neoplasms
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Humans
  • Combined Modality Therapy
  • Clinical Trials as Topic
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis