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Dextroamphetamine-induced changes in regional cerebral blood flow

Publication ,  Journal Article
Mathew, RJ; Wilson, WH
Published in: Psychopharmacology
1985

Regional cerebral blood flow (CBF), blood pressure, pulse rate, respiratory rate, end-tidal carbon dioxide and mood states were measured before and after IV injections of 15 mg dextroamphetamine sulfate or saline in 22 physically and mentally healthy normal volunteers. Amphetamine administration was associated with significant increases in systolic blood pressure and vigor and decrease in end-tidal carbon dioxide. There were no significant differences between the amphetamine and saline groups on CBF changes. However, there was a non-significant trend towards a post-amphetamine CBF reduction, even after the flow values were corrected for the acute changes in CO2.

Duke Scholars

Published In

Psychopharmacology

Publication Date

1985

Volume

87

Issue

3

Start / End Page

298 / 302

Related Subject Headings

  • Psychiatry
  • 17 Psychology and Cognitive Sciences
  • 11 Medical and Health Sciences
 

Citation

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Mathew, R. J., & Wilson, W. H. (1985). Dextroamphetamine-induced changes in regional cerebral blood flow. Psychopharmacology, 87(3), 298–302.
Mathew, R. J., and W. H. Wilson. “Dextroamphetamine-induced changes in regional cerebral blood flow.” Psychopharmacology 87, no. 3 (1985): 298–302.
Mathew RJ, Wilson WH. Dextroamphetamine-induced changes in regional cerebral blood flow. Psychopharmacology. 1985;87(3):298–302.
Mathew, R. J., and W. H. Wilson. “Dextroamphetamine-induced changes in regional cerebral blood flow.” Psychopharmacology, vol. 87, no. 3, 1985, pp. 298–302.
Mathew RJ, Wilson WH. Dextroamphetamine-induced changes in regional cerebral blood flow. Psychopharmacology. 1985;87(3):298–302.

Published In

Psychopharmacology

Publication Date

1985

Volume

87

Issue

3

Start / End Page

298 / 302

Related Subject Headings

  • Psychiatry
  • 17 Psychology and Cognitive Sciences
  • 11 Medical and Health Sciences