The effect of nonsedating doses of diazepam on regional cerebral blood flow
Publication
, Journal Article
Mathew, RJ; Wilson, WH; Daniel, DG
Published in: Biological Psychiatry
1985
Drugs like diazepam induce tranquilization in small doses and sedation in larger quanitities. Regional cerebral blood flow (rCBF) was measured before and 5 min after the intravenous administraton of nonsedating doses of diazepam or placebo (given on a double-blind basis) to 20 right-handed volunteers. Subjects who received diazepam showed marked right hemispheric rCBF decreases, especially in the frontal lobe, whereas controls did not show significant differences between the two sets of values. None of the subjects became sleepy during the experiment.
Duke Scholars
Published In
Biological Psychiatry
Publication Date
1985
Volume
20
Issue
10
Start / End Page
1109 / 1116
Related Subject Headings
- Psychiatry
- 17 Psychology and Cognitive Sciences
- 11 Medical and Health Sciences
- 06 Biological Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Mathew, R. J., Wilson, W. H., & Daniel, D. G. (1985). The effect of nonsedating doses of diazepam on regional cerebral blood flow. Biological Psychiatry, 20(10), 1109–1116.
Mathew, R. J., W. H. Wilson, and D. G. Daniel. “The effect of nonsedating doses of diazepam on regional cerebral blood flow.” Biological Psychiatry 20, no. 10 (1985): 1109–16.
Mathew RJ, Wilson WH, Daniel DG. The effect of nonsedating doses of diazepam on regional cerebral blood flow. Biological Psychiatry. 1985;20(10):1109–16.
Mathew, R. J., et al. “The effect of nonsedating doses of diazepam on regional cerebral blood flow.” Biological Psychiatry, vol. 20, no. 10, 1985, pp. 1109–16.
Mathew RJ, Wilson WH, Daniel DG. The effect of nonsedating doses of diazepam on regional cerebral blood flow. Biological Psychiatry. 1985;20(10):1109–1116.
Published In
Biological Psychiatry
Publication Date
1985
Volume
20
Issue
10
Start / End Page
1109 / 1116
Related Subject Headings
- Psychiatry
- 17 Psychology and Cognitive Sciences
- 11 Medical and Health Sciences
- 06 Biological Sciences