Possible lack of anticholinergic effects with mianserin: A pilot study

Journal Article

Anticholinergic effects of mianserin, a new tetracyclic antidepressant, were studied in 5 depressed patients. Prior to and after 1 and 2 hours of the administration of 30 mg of mianserin salivary flow, pupillary response to light and palpebral fissure were measured. Analysis of data revealed a statistically significant decrease in pupil diameter. There was no change in palpebral fissure size. Possible clinical implications of these findings are discussed.

Duke Authors

Cited Authors

  • Wilson, WH; Petrie, WM; Ban, TA

Published Date

  • 1980

Published In

  • Journal of Clinical Psychiatry

Volume / Issue

  • 41 / 2

Start / End Page

  • 63 - 65