Mianserin: Determination of therapeutic dose range
Publication
, Journal Article
Petrie, WM; Wilson, WH; Ban, TA; Guy, W; Schaffer, JD
Published in: International Pharmacopsychiatry
1980
Mianserin hydrochloride is a tetracyclic antidepressant with an EEG and clinical activity profile similar to amitriptyline. To investigate the drug's optimal dosage range, a 6-week open comparative trial sequentially assigned 12 depressed patients to one of three dose ranges (60, 90 and 120 mg). Improvement occurred in depressive symptomatology in all three treatment groups. There was no differential improvement noted in any group; however, the incidence of adverse effects was greater in the middle (90 mg) and high (120 mg) dose ranges.
Duke Scholars
Published In
International Pharmacopsychiatry
ISSN
0020-8272
Publication Date
1980
Volume
15
Issue
2
Start / End Page
111 / 117
Related Subject Headings
- Psychiatry
- 1702 Cognitive Sciences
- 1109 Neurosciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Petrie, W. M., Wilson, W. H., Ban, T. A., Guy, W., & Schaffer, J. D. (1980). Mianserin: Determination of therapeutic dose range. International Pharmacopsychiatry, 15(2), 111–117.
Petrie, W. M., W. H. Wilson, T. A. Ban, W. Guy, and J. D. Schaffer. “Mianserin: Determination of therapeutic dose range.” International Pharmacopsychiatry 15, no. 2 (1980): 111–17.
Petrie WM, Wilson WH, Ban TA, Guy W, Schaffer JD. Mianserin: Determination of therapeutic dose range. International Pharmacopsychiatry. 1980;15(2):111–7.
Petrie, W. M., et al. “Mianserin: Determination of therapeutic dose range.” International Pharmacopsychiatry, vol. 15, no. 2, 1980, pp. 111–17.
Petrie WM, Wilson WH, Ban TA, Guy W, Schaffer JD. Mianserin: Determination of therapeutic dose range. International Pharmacopsychiatry. 1980;15(2):111–117.
Published In
International Pharmacopsychiatry
ISSN
0020-8272
Publication Date
1980
Volume
15
Issue
2
Start / End Page
111 / 117
Related Subject Headings
- Psychiatry
- 1702 Cognitive Sciences
- 1109 Neurosciences
- 1103 Clinical Sciences