The impact of steatosis and alcohol on hepatitis C


Journal Article (Review)

Alcohol consumption and hepatic steatosis interact synergistically with hepatitis C virus (HCV) to accelerate fibrosis progression and reduce the efficacy of standard antiviral therapies. Research aimed at delineating the viral and host interactions involved in the pathogenesis of steatosis in HCV infection may provide novel therapeutic strategies that can modify disease progression and improve treatment response. This review discusses the clinical aspects of HCV fibrosis progression and treatment response in the setting of alcohol use or hepatic steatosis. Copyright © 2007 by Current Medicine Group LLC.

Full Text

Duke Authors

Cited Authors

  • Galhenage, S; Abdelmalek, MF

Published Date

  • January 1, 2007

Published In

Volume / Issue

  • 6 / 2

Start / End Page

  • 39 - 45

Electronic International Standard Serial Number (EISSN)

  • 1541-0706

International Standard Serial Number (ISSN)

  • 1540-3416

Digital Object Identifier (DOI)

  • 10.1007/s11901-007-0002-y

Citation Source

  • Scopus