Mechanisms underlying nonalcoholic steatohepatitis


Journal Article (Review)

Nonalcoholic fatty liver disease (NAFLD), a spectrum of liver damage, encompasses steatosis, steatohepatitis, an intermediate stage of liver disease and cirrhosis. Although NAFLD is the leading cause of chronic liver disease, no effective therapies currently exist. Complex interactions between injury and repair mechanisms likely determine disease progression in NAFLD. The development of successful treatments for NAFLD can be facilitated by understanding disease mechanisms. © 2006 Elsevier Ltd. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Abdelmalek, MF; Diehl, AM

Published Date

  • December 1, 2006

Published In

Volume / Issue

  • 3 / 4

Start / End Page

  • 479 - 488

International Standard Serial Number (ISSN)

  • 1740-6765

Digital Object Identifier (DOI)

  • 10.1016/j.ddmec.2006.11.001

Citation Source

  • Scopus