Methyl parathion: a review of health effects.


Journal Article (Review)

Methyl parathion is an organophosphorus (OP) insecticide with insecticidal properties derived from acetylcholinesterase (AChE) inhibition; this same property is also the root of its toxicity in humans. Poisoning with methyl parathion leads to cholinergic overstimulation with signs of toxicity including sweating, dizziness, vomiting, diarrhea, convulsions, cardiac arrest, respiratory arrest, and, in extreme cases, death. Reports of methyl parathion intoxication, usually seen only in field pesticide applicators, have increased throughout the United States as a result of unauthorized application of methyl parathion inside homes. The health concerns of the use of methyl parathion have resulted in cancellation of its use in most food crops in the United States. This review examines the well-documented neurotoxicity of methyl parathion as well as effects on other organ systems.

Full Text

Duke Authors

Cited Authors

  • Garcia, SJ; Abu-Qare, AW; Meeker-O'Connell, WA; Borton, AJ; Abou-Donia, MB

Published Date

  • March 2003

Published In

Volume / Issue

  • 6 / 2

Start / End Page

  • 185 - 210

PubMed ID

  • 12554434

Pubmed Central ID

  • 12554434

International Standard Serial Number (ISSN)

  • 1093-7404

Digital Object Identifier (DOI)

  • 10.1080/10937400306471


  • eng

Conference Location

  • England