Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis.
Journal Academic Article, Research Support, N.I.H., Extramural
Osteoarthritis (OA) results in pain and disability; however, preclinical OA models often focus on joint-level changes. Gait analysis is one method used to evaluate both preclinical OA models and OA patients. The objective of this study is to describe spatiotemporal and ground reaction force changes in a rat medial meniscus transection (MMT) model of knee OA and to compare these gait measures with assays of weight bearing and tactile allodynia.
Allen, KD; Mata, BA; Gabr, MA; Huebner, JL; Adams, SB; Kraus, VB; Schmitt, DO; Setton, LA
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