Balancing acts: molecular control of mammalian iron metabolism.

Journal Article (Review)

Iron is ubiquitous in the environment and in biology. The study of iron biology focuses on physiology and homeostasis-understanding how cells and organisms regulate their iron content, how diverse tissues orchestrate iron allocation, and how dysregulated iron homeostasis leads to common hematological, metabolic, and neurodegenerative diseases. This has provided novel insights into gene regulation and unveiled remarkable links to the immune system.

Full Text

Duke Authors

Cited Authors

  • Hentze, MW; Muckenthaler, MU; Andrews, NC

Published Date

  • April 30, 2004

Published In

Volume / Issue

  • 117 / 3

Start / End Page

  • 285 - 297

PubMed ID

  • 15109490

Pubmed Central ID

  • 15109490

International Standard Serial Number (ISSN)

  • 0092-8674

Digital Object Identifier (DOI)

  • 10.1016/s0092-8674(04)00343-5

Language

  • eng

Conference Location

  • United States