Anemia of inflammation: the cytokine-hepcidin link.
Journal Article
The anemia of inflammation, commonly observed in patients with chronic infections, malignancy, trauma, and inflammatory disorders, is a well-known clinical entity. Until recently, we understood little about its pathogenesis. It now appears that the inflammatory cytokine IL-6 induces production of hepcidin, an iron-regulatory hormone that may be responsible for most or all of the features of this disorder.
Full Text
Duke Authors
Cited Authors
- Andrews, NC
Published Date
- May 2004
Published In
Volume / Issue
- 113 / 9
Start / End Page
- 1251 - 1253
PubMed ID
- 15124013
Pubmed Central ID
- 15124013
International Standard Serial Number (ISSN)
- 0021-9738
Digital Object Identifier (DOI)
- 10.1172/JCI21441
Language
- eng
Conference Location
- United States