Anemia of inflammation: the cytokine-hepcidin link.

Journal Article (Journal Article)

The anemia of inflammation, commonly observed in patients with chronic infections, malignancy, trauma, and inflammatory disorders, is a well-known clinical entity. Until recently, we understood little about its pathogenesis. It now appears that the inflammatory cytokine IL-6 induces production of hepcidin, an iron-regulatory hormone that may be responsible for most or all of the features of this disorder.

Full Text

Duke Authors

Cited Authors

  • Andrews, NC

Published Date

  • May 2004

Published In

Volume / Issue

  • 113 / 9

Start / End Page

  • 1251 - 1253

PubMed ID

  • 15124013

Pubmed Central ID

  • PMC398435

International Standard Serial Number (ISSN)

  • 0021-9738

Digital Object Identifier (DOI)

  • 10.1172/JCI21441

Language

  • eng

Conference Location

  • United States