A genetic view of iron homeostasis.

Journal Article (Journal Article;Review)

Inherited disorders of iron metabolism are invariably disorders of iron balance or distribution. This review describes the proteins known to be involved in establishing and maintaining iron balance, and discusses regulation of iron homeostasis in the context of three cell types: intestinal enterocytes, reticuloendothelial macrophages, and hepatocytes. It emphasizes information gleaned from the use of genetic analyses, particularly in mice, and poses new questions to help advance our understanding of iron balance.

Full Text

Duke Authors

Cited Authors

  • Andrews, NC

Published Date

  • October 2002

Published In

Volume / Issue

  • 39 / 4

Start / End Page

  • 227 - 234

PubMed ID

  • 12382197

International Standard Serial Number (ISSN)

  • 0037-1963

Digital Object Identifier (DOI)

  • 10.1053/shem.2002.35632


  • eng

Conference Location

  • United States