Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.


Journal Article

Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.

Full Text

Duke Authors

Cited Authors

  • Andrews, NC; Erdjument-Bromage, H; Davidson, MB; Tempst, P; Orkin, SH

Published Date

  • April 22, 1993

Published In

Volume / Issue

  • 362 / 6422

Start / End Page

  • 722 - 728

PubMed ID

  • 8469283

Pubmed Central ID

  • 8469283

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/362722a0


  • eng

Conference Location

  • England