Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.

Journal Article (Journal Article)

Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.

Full Text

Duke Authors

Cited Authors

  • Andrews, NC; Erdjument-Bromage, H; Davidson, MB; Tempst, P; Orkin, SH

Published Date

  • April 22, 1993

Published In

Volume / Issue

  • 362 / 6422

Start / End Page

  • 722 - 728

PubMed ID

  • 8469283

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/362722a0


  • eng

Conference Location

  • England