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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.

Publication ,  Journal Article
Andrews, NC; Erdjument-Bromage, H; Davidson, MB; Tempst, P; Orkin, SH
Published in: Nature
April 22, 1993

Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.

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Published In

Nature

DOI

ISSN

0028-0836

Publication Date

April 22, 1993

Volume

362

Issue

6422

Start / End Page

722 / 728

Location

England

Related Subject Headings

  • Zinc Fingers
  • Tumor Cells, Cultured
  • Transfection
  • Transcription Factors
  • Peptides
  • NF-E2 Transcription Factor, p45 Subunit
  • NF-E2 Transcription Factor
  • Mutation
  • Molecular Sequence Data
  • Mice
 

Citation

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Andrews, N. C., Erdjument-Bromage, H., Davidson, M. B., Tempst, P., & Orkin, S. H. (1993). Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature, 362(6422), 722–728. https://doi.org/10.1038/362722a0
Andrews, N. C., H. Erdjument-Bromage, M. B. Davidson, P. Tempst, and S. H. Orkin. “Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.Nature 362, no. 6422 (April 22, 1993): 722–28. https://doi.org/10.1038/362722a0.
Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature. 1993 Apr 22;362(6422):722–8.
Andrews, N. C., et al. “Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.Nature, vol. 362, no. 6422, Apr. 1993, pp. 722–28. Pubmed, doi:10.1038/362722a0.
Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature. 1993 Apr 22;362(6422):722–728.
Journal cover image

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

April 22, 1993

Volume

362

Issue

6422

Start / End Page

722 / 728

Location

England

Related Subject Headings

  • Zinc Fingers
  • Tumor Cells, Cultured
  • Transfection
  • Transcription Factors
  • Peptides
  • NF-E2 Transcription Factor, p45 Subunit
  • NF-E2 Transcription Factor
  • Mutation
  • Molecular Sequence Data
  • Mice