Lack of evidence for VPg priming of poliovirus RNA synthesis in the host factor-dependent in vitro replicase reaction.

Journal Article (Journal Article)

Anti-VPg immunoprecipitable RNA labeled in vitro during a poliovirus RNA polymerase reaction was formed by the elongation of VPg-containing template fragments rather than by initiation with VPg. The reaction was dependent on a host factor (terminal uridylyl transferase). The incorporation of labeled UTP could be detected with only the host factor present.

Full Text

Duke Authors

Cited Authors

  • Andrews, NC; Baltimore, D

Published Date

  • April 1986

Published In

Volume / Issue

  • 58 / 1

Start / End Page

  • 212 - 215

PubMed ID

  • 3005650

Pubmed Central ID

  • PMC252895

International Standard Serial Number (ISSN)

  • 0022-538X

Digital Object Identifier (DOI)

  • 10.1128/JVI.58.1.212-215.1986


  • eng

Conference Location

  • United States