Lack of evidence for VPg priming of poliovirus RNA synthesis in the host factor-dependent in vitro replicase reaction.
Published
Journal Article
Anti-VPg immunoprecipitable RNA labeled in vitro during a poliovirus RNA polymerase reaction was formed by the elongation of VPg-containing template fragments rather than by initiation with VPg. The reaction was dependent on a host factor (terminal uridylyl transferase). The incorporation of labeled UTP could be detected with only the host factor present.
Full Text
Duke Authors
Cited Authors
- Andrews, NC; Baltimore, D
Published Date
- April 1986
Published In
Volume / Issue
- 58 / 1
Start / End Page
- 212 - 215
PubMed ID
- 3005650
Pubmed Central ID
- 3005650
International Standard Serial Number (ISSN)
- 0022-538X
Language
- eng
Conference Location
- United States