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The health education for lupus study: a randomized controlled cognitive-behavioral intervention targeting psychosocial adjustment and quality of life in adolescent females with systemic lupus erythematosus.

Publication ,  Journal Article
Brown, RT; Shaftman, SR; Tilley, BC; Anthony, KK; Kral, MC; Maxson, B; Mee, L; Bonner, MJ; Vogler, LB; Schanberg, LE; Connelly, MA; Wagner, JL ...
Published in: Am J Med Sci
October 2012

INTRODUCTION: To examine in a randomize controlled feasibility clinical trial the efficacy of a cognitive-behavioral intervention designed to manage pain, enhance disease adjustment and adaptation and improve quality of life among female adolescents with systemic lupus erythematosus. METHODS: Female adolescents (n = 53) ranging in age from 12 to 18 years were randomly assigned to 1 of 3 groups including a cognitive-behavioral intervention, an education-only arm and a no-contact control group. Participants were assessed at baseline, postintervention and at 3- and 6-month intervals after completion of the intervention. RESULTS: No significant differences were revealed among the 3 treatment arms for any of the dependent measures at any of the assessment points. For the mediator variables, a posthoc secondary analysis did reveal increases in coping skills from baseline to postintervention among the participants in the cognitive-behavioral intervention group compared with both the no-contact control group and the education-only group. CONCLUSION: Although no differences were detected in the primary outcome, a possible effect on coping of female adolescents with systemic lupus erythematosus was detected in this feasibility study. Whether the impact of training in the area of coping was of sufficient magnitude to generalize to other areas of functioning, such as adjustment and adaptation, is unclear. Future phase III randomized trials will be needed to assess additional coping models and to evaluate the dose of training and its influence on pain management, adjustment and health-related quality of life.

Duke Scholars

Published In

Am J Med Sci

DOI

EISSN

1538-2990

Publication Date

October 2012

Volume

344

Issue

4

Start / End Page

274 / 282

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Social Adjustment
  • Quality of Life
  • Pain Management
  • Pain
  • Lupus Erythematosus, Systemic
  • Humans
  • Health Education
  • General & Internal Medicine
  • Female
 

Citation

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Chicago
ICMJE
MLA
NLM
Brown, R. T., Shaftman, S. R., Tilley, B. C., Anthony, K. K., Kral, M. C., Maxson, B., … Nietert, P. J. (2012). The health education for lupus study: a randomized controlled cognitive-behavioral intervention targeting psychosocial adjustment and quality of life in adolescent females with systemic lupus erythematosus. Am J Med Sci, 344(4), 274–282. https://doi.org/10.1097/MAJ.0b013e3182449be9
Brown, Ronald T., Stephanie R. Shaftman, Barbara C. Tilley, Kelly K. Anthony, Mary C. Kral, Bonnie Maxson, Laura Mee, et al. “The health education for lupus study: a randomized controlled cognitive-behavioral intervention targeting psychosocial adjustment and quality of life in adolescent females with systemic lupus erythematosus.Am J Med Sci 344, no. 4 (October 2012): 274–82. https://doi.org/10.1097/MAJ.0b013e3182449be9.
Brown RT, Shaftman SR, Tilley BC, Anthony KK, Kral MC, Maxson B, Mee L, Bonner MJ, Vogler LB, Schanberg LE, Connelly MA, Wagner JL, Silver RM, Nietert PJ. The health education for lupus study: a randomized controlled cognitive-behavioral intervention targeting psychosocial adjustment and quality of life in adolescent females with systemic lupus erythematosus. Am J Med Sci. 2012 Oct;344(4):274–282.
Journal cover image

Published In

Am J Med Sci

DOI

EISSN

1538-2990

Publication Date

October 2012

Volume

344

Issue

4

Start / End Page

274 / 282

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Social Adjustment
  • Quality of Life
  • Pain Management
  • Pain
  • Lupus Erythematosus, Systemic
  • Humans
  • Health Education
  • General & Internal Medicine
  • Female