Nocturnal penile tumescence in cigarette smokers with erectile dysfunction.

Journal Article (Journal Article)

We examined the relationship between cigarette smoking and erectile physiology in 314 men with erectile dysfunction. All of the men studied were currently cigarette smokers. Evaluations included interviews, physical examinations, and polysomnographic assessment of sleep-related erections. Penile rigidity during nocturnal erection inversely correlated with the number of cigarettes smoked per day. Smoking was also associated with indices of impairment on autonomic function tests and some measures of penile blood pressure. The group of men who smoked the most (more than 40 cigarettes per day) had the fewest minutes of nocturnal tumescence and detumesced fastest. These data are discussed with respect to the results of studies performed in dogs that demonstrated smoking-related reduction in arterial flow and venous restriction. Our findings suggest that smoking may further compromise penile physiology in men experiencing difficulty in maintaining erections long enough for satisfactory intercourse.

Full Text

Duke Authors

Cited Authors

  • Hirshkowitz, M; Karacan, I; Howell, JW; Arcasoy, MO; Williams, RL

Published Date

  • February 1, 1992

Published In

Volume / Issue

  • 39 / 2

Start / End Page

  • 101 - 107

PubMed ID

  • 1736499

International Standard Serial Number (ISSN)

  • 0090-4295

Digital Object Identifier (DOI)

  • 10.1016/0090-4295(92)90263-v


  • eng

Conference Location

  • United States