Fenoldopam: a new parenteral antihypertensive: consensus roundtable on the management of perioperative hypertension and hypertensive crises.


Other Article (Review)

A panel of clinicians from anesthesiology, surgery, nephrology, hypertension, cardiology, and pharmacology was convened to discuss pharmacologic therapeutics in the management of hypertensive crisis and perioperative hypertension. The panel discussed the advantages and limitations of currently available parenteral drugs, and assessed the potential use of fenoldopam mesylate, a drug in clinical development since 1981, and recently approved by the U.S. Food and Drug Administration (FDA). Fenoldopam is a dopamine receptor (DA1 selective) agonist that is a systemic and renal vasodilator. It was concluded that fenoldopam offers significant advantages as a parenterally administered agent for the management of blood pressure in both hypertensive emergencies and in the perioperative setting.

Full Text

Duke Authors

Cited Authors

  • Oparil, S; Aronson, S; Deeb, GM; Epstein, M; Levy, JH; Luther, RR; Prielipp, R; Taylor, A

Published Date

  • July 1999

Published In

Volume / Issue

  • 12 / 7

Start / End Page

  • 653 - 664

PubMed ID

  • 10411362

Pubmed Central ID

  • 10411362

International Standard Serial Number (ISSN)

  • 0895-7061

Digital Object Identifier (DOI)

  • 10.1016/s0895-7061(99)00059-x


  • eng

Conference Location

  • United States