Ultrasound densitometric analysis: Comparison between an online digital acquisition acoustic program and an offline analog program

Published

Journal Article

Videodensitometric analysis of myocardial contrast echocardiography is traditionally performed off line. Recently, an online contrast ultrasound analysis system, Acoustic Densitometry (Hewlett-Packard), was introduced. We compared pixel intensities acquired with Acoustic Densitometry to pixel intensities derived from videodensitometry. A tissue phantom was imaged in phase I using three transducer frequencies (2.5, 3.5, and 5.0 MHz). In phase II, an in vitro flowing tube model with various concentrations of Albunex® was imaged at two flow rates, 0.6 and 1.2 m/sec, and at two transducer frequencies, 2.5 and 3.5 MHz. The relationship between pixel intensities yielded by the two systems for identical ultrasound signals was determined with linear regression. Intensities derived with Acoustic Densitometry strongly correlated with those derived from the offline videodensitometry system. The intensities were related by a predictive multiplicative factor based on display characteristics of the two systems. These results suggest that semiquantitative, online perfusion analysis with Acoustic Densitometry is as sensitive as analysis offline with videodensitometry.

Duke Authors

Cited Authors

  • Fernandez, AP; Aronson, S; Toledano, A; Winkelmann, J; Saldivar, J; Feinstein, SB

Published Date

  • October 19, 1996

Published In

Volume / Issue

  • 13 / 5

Start / End Page

  • 489 - 497

International Standard Serial Number (ISSN)

  • 0742-2822

Citation Source

  • Scopus