Association of preoperative risk factors with postoperative acute renal failure.


Journal Article (Review)

We performed a systematic review of 28 studies that examined preoperative risk factors for postoperative renal failure. Included in the studies were 10,865 patients who underwent either vascular, cardiac, general, or biliary surgery. No two studies used the same criteria for acute renal failure. Variability in definitions of renal failure, lack of consistent criteria for establishing risk factors, and nonuniformity in the statistical methods employed result in a literature that is not adequate to support a comprehensive quantitative review. Of the 30 variables considered in the studies, preoperative renal risk factors, such as increased serum creatinine, increased blood urea nitrogen, and preoperative renal dysfunction were repeatedly found to predict postoperative renal dysfunction. The literature provides little quantitative information concerning the degree of risk associated with other factors. Cardiac risk factors, such as left ventricular dysfunction, were reported to be predictive of postoperative renal failure more consistently than was advanced age.

Full Text

Duke Authors

Cited Authors

  • Novis, BK; Roizen, MF; Aronson, S; Thisted, RA

Published Date

  • January 1, 1994

Published In

Volume / Issue

  • 78 / 1

Start / End Page

  • 143 - 149

PubMed ID

  • 8267150

Pubmed Central ID

  • 8267150

International Standard Serial Number (ISSN)

  • 0003-2999

Digital Object Identifier (DOI)

  • 10.1213/00000539-199401000-00023


  • eng

Conference Location

  • United States