Repolarizing stimuli followed by calcium transmembrane currents

Published

Journal Article

Repolarizing stimuli applied during the plateau phase of a cardiac action potential do not always cause the membrane to return to a resting state Instead, the repolarizing stimulus may be followed immediately by a subsequent action potential. The subsequent action potential occurs even though the repolarizing stimulus returns the transmembrane potential to its resting level. This study used the DiFrancesco-Noble membrane model in a patch geometry to evaluate the membrane currents that initiated the subsequent action potential. These initiating currents were found to be predominantly calcium currents.

Duke Authors

Cited Authors

  • Barr, RC; Plonsey, R

Published Date

  • December 1, 1995

Published In

Volume / Issue

  • 17 / 1

Start / End Page

  • 15 - 16

International Standard Serial Number (ISSN)

  • 0589-1019

Citation Source

  • Scopus