Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.
Journal Article (Journal Article)
We have studied the reaction kinetics of ten manganese porphyrins, differing in their meso substituents, with peroxynitrite (ONOO-) and carbonate radical anion (CO3.) using stopped-flow and pulse radiolysis, respectively. Rate constants for the reactions of Mn(III) porphyrins with ONOO- ranged from 1 x 10(5) to 3.4 x 10(7) m(-1) s(-1) and correlated well with previously reported kinetic and thermodynamic data that reflect the resonance and inductive effects of the substituents on the porphyrin ring. Rate constants for the reactions of Mn(III) porphyrins with CO3. ranged from 2 x 10(8) to 1.2 x 10(9) m(-1)s(-1) at pH
Full Text
Duke Authors
Cited Authors
- Ferrer-Sueta, G; Vitturi, D; Batinic-Haberle, I; Fridovich, I; Goldstein, S; Czapski, G; Radi, R
Published Date
- July 25, 2003
Published In
Volume / Issue
- 278 / 30
Start / End Page
- 27432 - 27438
PubMed ID
- 12700236
International Standard Serial Number (ISSN)
- 0021-9258
Digital Object Identifier (DOI)
- 10.1074/jbc.M213302200
Language
- eng
Conference Location
- United States