Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

Journal Article (Journal Article)

We have studied the reaction kinetics of ten manganese porphyrins, differing in their meso substituents, with peroxynitrite (ONOO-) and carbonate radical anion (CO3.) using stopped-flow and pulse radiolysis, respectively. Rate constants for the reactions of Mn(III) porphyrins with ONOO- ranged from 1 x 10(5) to 3.4 x 10(7) m(-1) s(-1) and correlated well with previously reported kinetic and thermodynamic data that reflect the resonance and inductive effects of the substituents on the porphyrin ring. Rate constants for the reactions of Mn(III) porphyrins with CO3. ranged from 2 x 10(8) to 1.2 x 10(9) m(-1)s(-1) at pH

Full Text

Duke Authors

Cited Authors

  • Ferrer-Sueta, G; Vitturi, D; Batinic-Haberle, I; Fridovich, I; Goldstein, S; Czapski, G; Radi, R

Published Date

  • July 25, 2003

Published In

Volume / Issue

  • 278 / 30

Start / End Page

  • 27432 - 27438

PubMed ID

  • 12700236

International Standard Serial Number (ISSN)

  • 0021-9258

Digital Object Identifier (DOI)

  • 10.1074/jbc.M213302200

Language

  • eng

Conference Location

  • United States