Molecular recognition of stable metal complexes through second-sphere coordination by macrocycles

Journal Article (Journal Article)

An investigation of second coordination shell complexation of ferrioxamine B by crown ethers, natural ionophores, and other macrocycles through host-guest complexation of the pendant protonated amine group is presented. The influence of guest structure, host structure, solvation shell, and counter ion on host-guest assembly stability is discussed. Application of this form of molecular recognition to bulk liquid membrane transport of a stable metal complex is also presented. The significance of ionophore recognition of a metal complex in the context of iron bioavailability is discussed.

Full Text

Duke Authors

Cited Authors

  • Crumbliss, AL; Batinić-Haberle, I; Spasojević, I

Published Date

  • January 1, 1996

Published In

Volume / Issue

  • 68 / 6

Start / End Page

  • 1225 - 1230

International Standard Serial Number (ISSN)

  • 0033-4545

Digital Object Identifier (DOI)

  • 10.1351/pac199668061225

Citation Source

  • Scopus