Skip to main content

Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias.

Publication ,  Journal Article
Bae-Jump, VL; Bauer, M; Van Le, L
Published in: J Low Genit Tract Dis
January 2007

OBJECTIVE: To determine whether cytological smears of the vulva correlate with vulvar biopsies of vulvar intraepithelial neoplasias (VINs). MATERIALS AND METHODS: A retrospective chart review (1995-2000) was performed to identify cases of VIN and vulvar carcinoma and to correlate vulvar Pap smears with biopsy results. RESULTS: Four hundred vulvar Pap smears were identified. Fifty of these patients had concomitant vulvar biopsies, and these cases constitute our study group. Twenty-two of these 50 women had biopsy-proven VIN or vulvar carcinoma. Only 7 (32%) of 22 patients with biopsy-proven disease had a vulvar Pap smear significant for VIN or vulvar carcinoma. The kappa statistic was 0.30 (95% CI=0.08-0.52), indicating poor agreement between vulvar cytology and biopsy results. CONCLUSIONS: Vulvar cytological evaluation did not correlate well with tissue diagnosis of VIN; and thus, our findings do not support the use of vulvar cytology in the clinical management of VIN.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Low Genit Tract Dis

DOI

ISSN

1089-2591

Publication Date

January 2007

Volume

11

Issue

1

Start / End Page

8 / 11

Location

United States

Related Subject Headings

  • Vulvar Neoplasms
  • Vaginal Smears
  • Retrospective Studies
  • Precancerous Conditions
  • Papanicolaou Test
  • Obstetrics & Reproductive Medicine
  • Humans
  • Female
  • Carcinoma in Situ
  • Biopsy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bae-Jump, V. L., Bauer, M., & Van Le, L. (2007). Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias. J Low Genit Tract Dis, 11(1), 8–11. https://doi.org/10.1097/01.lgt.0000229566.57482.f3
Bae-Jump, Victoria L., Maureen Bauer, and Linda Van Le. “Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias.J Low Genit Tract Dis 11, no. 1 (January 2007): 8–11. https://doi.org/10.1097/01.lgt.0000229566.57482.f3.
Bae-Jump VL, Bauer M, Van Le L. Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias. J Low Genit Tract Dis. 2007 Jan;11(1):8–11.
Bae-Jump, Victoria L., et al. “Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias.J Low Genit Tract Dis, vol. 11, no. 1, Jan. 2007, pp. 8–11. Pubmed, doi:10.1097/01.lgt.0000229566.57482.f3.
Bae-Jump VL, Bauer M, Van Le L. Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias. J Low Genit Tract Dis. 2007 Jan;11(1):8–11.

Published In

J Low Genit Tract Dis

DOI

ISSN

1089-2591

Publication Date

January 2007

Volume

11

Issue

1

Start / End Page

8 / 11

Location

United States

Related Subject Headings

  • Vulvar Neoplasms
  • Vaginal Smears
  • Retrospective Studies
  • Precancerous Conditions
  • Papanicolaou Test
  • Obstetrics & Reproductive Medicine
  • Humans
  • Female
  • Carcinoma in Situ
  • Biopsy