Consumer perspectives on genetic testing for psychiatric disorders: the attitudes of veterans with posttraumatic stress disorder and their families.

Journal Article (Journal Article)

The perspectives of patients with posttraumatic stress disorder (PTSD) on genetic research have not yet been investigated in the genetics research literature. To provide a basis for research on attitudes toward genetic research in PTSD, we surveyed the U.S. Military Afghanistan/Iraq-era veterans with PTSD and their social support companions to investigate the attitudes and knowledge about genetics and genetic testing. One hundred forty-six veterans (76 with PTSD and 70 without PTSD) participated in this study. Each veteran participant had a corresponding companion (primarily spouses, but also relatives and friends) who they identified as a primary member of their social support network. Participants and companions completed self-report measures on knowledge of genetics and attitudes toward genetic testing for PTSD. Results indicated that, relative to veterans without PTSD, veterans with PTSD had similar levels of genetic knowledge, but less-favorable attitudes toward genetic testing. Differences persisted after controlling for age and genetics knowledge. No differences between companions of those with and without PTSD were observed. Results suggest that the perspective of those with PTSD regarding genetic testing is in need of further investigation, especially if potentially beneficial genetic testing for PTSD is to be utilized in the target population.

Full Text

Duke Authors

Cited Authors

  • Dedert, EA; Elbogen, EB; Hauser, MA; Hertzberg, JS; Wilson, SM; Dennis, MF; Calhoun, PS; Kirby, AC; Beckham, JC

Published Date

  • September 2012

Published In

Volume / Issue

  • 16 / 9

Start / End Page

  • 1122 - 1129

PubMed ID

  • 22891755

Pubmed Central ID

  • PMC3438836

Electronic International Standard Serial Number (EISSN)

  • 1945-0257

Digital Object Identifier (DOI)

  • 10.1089/gtmb.2012.0048


  • eng

Conference Location

  • United States