Structure of microtubules with reduced hydration. Comparison of results from X-ray diffraction and electron microscopy.

Journal Article (Journal Article)

A recent model for the structure of microtubules is used to interpret X-ray fiber diffraction patterns from microtubules, obtained under various conditions. The results suggest that tubulin may undergo conformational changes under conditions of reduced water-activity. Such changes could account for some of the differences in the structure of tubulin as determined by electron microscopy and X-ray diffraction.

Full Text

Duke Authors

Cited Authors

  • Beese, L; Stubbs, G; Thomas, J; Cohen, C

Published Date

  • August 5, 1987

Published In

Volume / Issue

  • 196 / 3

Start / End Page

  • 575 - 580

PubMed ID

  • 3681968

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1016/0022-2836(87)90033-7


  • eng

Conference Location

  • Netherlands