Secretion and movement of wingless protein in the epidermis of the Drosophila embryo.

Journal Article (Journal Article)

The segment polarity gene wingless encodes a cysteine rich protein which is essential for pattern formation in Drosophila. Using polyclonal antibodies against the product of the wingless gene, we demonstrate that this protein is secreted in the embryo and that it is taken up by neighbouring cells. The protein can be found two or three cell diameters away from the cells in which it is synthesized. We discuss the possible mechanisms which are responsible for this spatial distribution and its regulation during embryogenesis.

Full Text

Published version (via Digital Object Identifier)

Duke Authors

Bejsovec, Amy

Cited Authors

González, F; Swales, L; Bejsovec, A; Skaer, H; Martinez Arias, A

Published Date

August 1991

Published In

Mechanisms of Development

Volume / Issue

35 / 1

Start / End Page

43 - 54

PubMed ID

1720017

Electronic International Standard Serial Number (EISSN)

1872-6356

International Standard Serial Number (ISSN)

0925-4773

Digital Object Identifier (DOI)

10.1016/0925-4773(91)90040-d

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