Applying the PRECIS criteria to describe three effectiveness trials of weight loss in obese patients with comorbid conditions.
Journal Article (Journal Article)
Objectives
To characterize Practice-Based Opportunities for Weight Reduction (POWER) trials along the pragmatic-explanatory continuum.Settings
The POWER trials consist of three individual studies that target obesity treatment in primary care settings.Design
Using the PRagmatic Explanatory Continuum Indicator Summary (PRECIS) criteria, nine reviewers independently scored each trial.Methods
Average and median ratings, inter-rater reliability, and relationships to additional ratings of the extent to which study designs were explanatory (i.e., efficacy) versus pragmatic (i.e., practical) and related to external validity were determined.Principal findings
One trial was consistently rated as being significantly more pragmatic than the others (R(2) =0.43, p< .001), although all three were in the moderate range on the PRECIS scales. Ratings varied across PRECIS dimensions, being most pragmatic on comparison condition and primary outcome. Raters, although undergoing training and using identical definitions, scored their own study as more pragmatic than the other studies/interventions.Conclusions
These results highlight the need for more comprehensive reporting on PRECIS and related criteria for research translation. The PRECIS criteria provide a richer understanding of the POWER studies. It is not clear whether the original criteria are sufficient to provide a comprehensive profile.Full Text
Duke Authors
Cited Authors
- Glasgow, RE; Gaglio, B; Bennett, G; Jerome, GJ; Yeh, H-C; Sarwer, DB; Appel, L; Colditz, G; Wadden, TA; Wells, B
Published Date
- June 2012
Published In
Volume / Issue
- 47 / 3 Pt 1
Start / End Page
- 1051 - 1067
PubMed ID
- 22092292
Pubmed Central ID
- PMC3423177
Electronic International Standard Serial Number (EISSN)
- 1475-6773
International Standard Serial Number (ISSN)
- 0017-9124
Digital Object Identifier (DOI)
- 10.1111/j.1475-6773.2011.01347.x
Language
- eng