Defects in ankyrin-based cellular pathways in metazoan physiology.

Journal Article (Journal Article;Review)

Ankyrins are a ubiquitously expressed family of membrane-adaptor proteins found in most vertebrate tissues. Since the first ankyrin polypeptide was identified over 25 years ago, studies in humans, mice, and lower organisms have implicated critical roles for ankyrins in normal metazoan physiology. This review will provide an overview of the ankyrin family and highlight seminal findings in the field which have linked dysfunction in ankyrin-based pathways with defects in metazoan physiology and human disease.

Full Text

Duke Authors

Cited Authors

  • Mohler, PJ; Bennett, V

Published Date

  • September 1, 2005

Published In

Volume / Issue

  • 10 /

Start / End Page

  • 2832 - 2840

PubMed ID

  • 15970537

International Standard Serial Number (ISSN)

  • 1093-9946

Digital Object Identifier (DOI)

  • 10.2741/1739

Language

  • eng

Conference Location

  • United States