The ANK repeat: a ubiquitous motif involved in macromolecular recognition.

Journal Article (Journal Article)

Many proteins rely on stable, noncovalent interactions with other macromolecules to perform their function. The identification of a repeated sequence motif, the ANK repeat, in diverse proteins whose common function involves binding to other proteins indicates one way nature may achieve a wide range of protein-protein interactions. In this article, we describe evidence that these ANK repeats are involved in the specific recognition of proteins and possibly DNA, and present a model for the folding of the motif.

Full Text

Duke Authors

Cited Authors

  • Michaely, P; Bennett, V

Published Date

  • May 1992

Published In

Volume / Issue

  • 2 / 5

Start / End Page

  • 127 - 129

PubMed ID

  • 14731966

Pubmed Central ID

  • 14731966

International Standard Serial Number (ISSN)

  • 0962-8924

Digital Object Identifier (DOI)

  • 10.1016/0962-8924(92)90084-z

Language

  • eng

Conference Location

  • England