The ANK repeat: a ubiquitous motif involved in macromolecular recognition.
Journal Article (Journal Article)
Many proteins rely on stable, noncovalent interactions with other macromolecules to perform their function. The identification of a repeated sequence motif, the ANK repeat, in diverse proteins whose common function involves binding to other proteins indicates one way nature may achieve a wide range of protein-protein interactions. In this article, we describe evidence that these ANK repeats are involved in the specific recognition of proteins and possibly DNA, and present a model for the folding of the motif.
Full Text
Duke Authors
Cited Authors
- Michaely, P; Bennett, V
Published Date
- May 1992
Published In
Volume / Issue
- 2 / 5
Start / End Page
- 127 - 129
PubMed ID
- 14731966
International Standard Serial Number (ISSN)
- 0962-8924
Digital Object Identifier (DOI)
- 10.1016/0962-8924(92)90084-z
Language
- eng
Conference Location
- England