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A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma.

Publication ,  Journal Article
DeBenedet, AT; Berg, CL; Enfield, KB; Woodford, RL; Bennett, AK; Northup, PG
Published in: Nat Clin Pract Gastroenterol Hepatol
January 2008

BACKGROUND: A 39-year-old man presented with a 2-month history of abdominal pain, jaundice, non-bloody diarrhea, weakness, and weight loss. Initial evaluation revealed intrahepatic ductopenia consistent with vanishing bile duct syndrome and IBD, type unclassified. Although treatment with budesonide improved his symptoms, they worsened several months later. On repeat evaluation, he was found to have extensive lymphadenopathy and an elevated white blood cell count. INVESTIGATIONS: Physical examination, laboratory investigations, abdominal ultrasound, CT scans, magnetic resonance cholangiopancreatography, endoscopic retrograde cholangiopancreatography, colonoscopies with biopsies, hepatic biopsy, axillary lymph node biopsy. DIAGNOSIS: Hodgkin's lymphoma with secondary vanishing bile duct syndrome and IBD, type unclassified. MANAGEMENT: The initial symptoms were managed with budesonide, but following recurrence, the patient's underlying lymphoma was treated with nitrogen mustard and dexamethasone.

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Published In

Nat Clin Pract Gastroenterol Hepatol

DOI

EISSN

1743-4386

Publication Date

January 2008

Volume

5

Issue

1

Start / End Page

49 / 53

Location

England

Related Subject Headings

  • Syndrome
  • Male
  • Inflammatory Bowel Diseases
  • Humans
  • Hodgkin Disease
  • Gastroenterology & Hepatology
  • Bile Duct Diseases
  • Adult
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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DeBenedet, A. T., Berg, C. L., Enfield, K. B., Woodford, R. L., Bennett, A. K., & Northup, P. G. (2008). A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma. Nat Clin Pract Gastroenterol Hepatol, 5(1), 49–53. https://doi.org/10.1038/ncpgasthep1001
DeBenedet, Anthony T., Carl L. Berg, Kyle B. Enfield, Randall L. Woodford, Audrey K. Bennett, and Patrick G. Northup. “A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma.Nat Clin Pract Gastroenterol Hepatol 5, no. 1 (January 2008): 49–53. https://doi.org/10.1038/ncpgasthep1001.
DeBenedet AT, Berg CL, Enfield KB, Woodford RL, Bennett AK, Northup PG. A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma. Nat Clin Pract Gastroenterol Hepatol. 2008 Jan;5(1):49–53.
DeBenedet, Anthony T., et al. “A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma.Nat Clin Pract Gastroenterol Hepatol, vol. 5, no. 1, Jan. 2008, pp. 49–53. Pubmed, doi:10.1038/ncpgasthep1001.
DeBenedet AT, Berg CL, Enfield KB, Woodford RL, Bennett AK, Northup PG. A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma. Nat Clin Pract Gastroenterol Hepatol. 2008 Jan;5(1):49–53.

Published In

Nat Clin Pract Gastroenterol Hepatol

DOI

EISSN

1743-4386

Publication Date

January 2008

Volume

5

Issue

1

Start / End Page

49 / 53

Location

England

Related Subject Headings

  • Syndrome
  • Male
  • Inflammatory Bowel Diseases
  • Humans
  • Hodgkin Disease
  • Gastroenterology & Hepatology
  • Bile Duct Diseases
  • Adult
  • 1103 Clinical Sciences