Volumetric brain imaging findings in mood disorders.

Journal Article (Journal Article;Review)

Volumetric neuroimaging is increasingly being used by researchers of affective disorders to assess potential involvement of different brain structures in mood regulation and to test neuroanatomic models of mood disorders. In unipolar depression, findings suggest abnormalities in the frontal lobe (particularly the subgenual prefrontal cortex), basal ganglia (particularly the caudate and putamen), cerebellum, and hippocampus/amygdala complex. In bipolar disorder, abnormalities in the third ventricle, frontal lobe, cerebellum, and possibly the temporal lobe are noted. We review the findings for the various regions of the brain, and discuss the implications on the understanding of mood disorders. Directions for future research in volumetric imaging is then discussed.

Full Text

Duke Authors

Cited Authors

  • Beyer, JL; Krishnan, KRR

Published Date

  • April 2002

Published In

Volume / Issue

  • 4 / 2

Start / End Page

  • 89 - 104

PubMed ID

  • 12071514

International Standard Serial Number (ISSN)

  • 1398-5647

Digital Object Identifier (DOI)

  • 10.1034/j.1399-5618.2002.01157.x


  • eng

Conference Location

  • Denmark