Volumetric brain imaging findings in mood disorders.
Volumetric neuroimaging is increasingly being used by researchers of affective disorders to assess potential involvement of different brain structures in mood regulation and to test neuroanatomic models of mood disorders. In unipolar depression, findings suggest abnormalities in the frontal lobe (particularly the subgenual prefrontal cortex), basal ganglia (particularly the caudate and putamen), cerebellum, and hippocampus/amygdala complex. In bipolar disorder, abnormalities in the third ventricle, frontal lobe, cerebellum, and possibly the temporal lobe are noted. We review the findings for the various regions of the brain, and discuss the implications on the understanding of mood disorders. Directions for future research in volumetric imaging is then discussed.
Duke Scholars
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Related Subject Headings
- Tomography, X-Ray Computed
- Psychiatry
- Mood Disorders
- Magnetic Resonance Imaging
- Humans
- Brain
- 4203 Health services and systems
- 3202 Clinical sciences
- 1109 Neurosciences
- 1103 Clinical Sciences
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Tomography, X-Ray Computed
- Psychiatry
- Mood Disorders
- Magnetic Resonance Imaging
- Humans
- Brain
- 4203 Health services and systems
- 3202 Clinical sciences
- 1109 Neurosciences
- 1103 Clinical Sciences