A prospective study of depression following combat deployment in support of the wars in Iraq and Afghanistan.

Journal Article (Journal Article)

OBJECTIVE: We investigated relations between deployment and new-onset depression among US service members recently deployed to the wars in Iraq and Afghanistan. METHODS: We included 40 219 Millennium Cohort Study participants who completed baseline and follow-up questionnaires and met inclusion criteria. Participants were identified with depression if they met the Primary Care Evaluation of Mental Disorders Patient Health Questionnaire criteria for depression at follow-up, but not at baseline. RESULTS: Deployed men and women with combat exposures had the highest onset of depression, followed by those not deployed and those deployed without combat exposures. Combat-deployed men and women were at increased risk for new-onset depression compared with nondeployed men and women (men: adjusted odds ratio [AOR]=1.32; 95% confidence interval [CI]=1.13, 1.54; women: AOR=2.13; 95% CI=1.70, 2.65). Conversely, deployment without combat exposures led to decreased risk for new-onset depression compared with those who did not deploy (men: AOR=0.66; 95% CI=0.53, 0.83; women: AOR=0.65; 95% CI=0.47, 0.89). CONCLUSIONS: Deployment with combat exposures is a risk factor for new-onset depression among US service members. Post-deployment screening may be beneficial for US service members exposed to combat.

Full Text

Duke Authors

Cited Authors

  • Wells, TS; LeardMann, CA; Fortuna, SO; Smith, B; Smith, TC; Ryan, MAK; Boyko, EJ; Blazer, D; Millennium Cohort Study Team,

Published Date

  • January 2010

Published In

Volume / Issue

  • 100 / 1

Start / End Page

  • 90 - 99

PubMed ID

  • 19910353

Pubmed Central ID

  • PMC2791239

Electronic International Standard Serial Number (EISSN)

  • 1541-0048

Digital Object Identifier (DOI)

  • 10.2105/AJPH.2008.155432


  • eng

Conference Location

  • United States