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Management of depression in patients with coronary heart disease: association, mechanisms, and treatment implications for depressed cardiac patients.

Publication ,  Journal Article
Wang, JT; Hoffman, B; Blumenthal, JA
Published in: Expert Opin Pharmacother
January 2011

IMPORTANCE OF THE FIELD: Coronary heart disease (CHD) and depression are two leading causes of death and disability in the United States and worldwide. Depression is especially common in cardiac patients, and there is growing evidence that depression is a risk factor for fatal and nonfatal events in CHD patients. AREAS COVERED IN THIS REVIEW: This paper reviews current literature of depression as a risk factor for CHD along with pharmacologic and non-pharmacologic treatments for depression in cardiac patients. WHAT THE READER WILL GAIN: Readers will gain knowledge about the importance of depression as a CHD risk factor and learn the results of efforts to treat depressed CHD patients. TAKE HOME MESSAGE: Although randomized clinical trials (RCTs) of medication and non-pharmacologic therapies have not demonstrated that treating depression improves survival, there is evidence that treating depressed patients can reduce depressive symptoms and improve quality of life. Additional RCTs are needed, including evaluation of non-pharmacologic therapies such as exercise, to examine the effects of treatment of depression on medical and psychosocial outcomes.

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Published In

Expert Opin Pharmacother

DOI

EISSN

1744-7666

Publication Date

January 2011

Volume

12

Issue

1

Start / End Page

85 / 98

Location

England

Related Subject Headings

  • Risk Factors
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Exercise Therapy
  • Depression
  • Cost of Illness
  • Coronary Disease
  • Antidepressive Agents
 

Citation

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Wang, J. T., Hoffman, B., & Blumenthal, J. A. (2011). Management of depression in patients with coronary heart disease: association, mechanisms, and treatment implications for depressed cardiac patients. Expert Opin Pharmacother, 12(1), 85–98. https://doi.org/10.1517/14656566.2010.513701
Wang, Jenny T., Benson Hoffman, and James A. Blumenthal. “Management of depression in patients with coronary heart disease: association, mechanisms, and treatment implications for depressed cardiac patients.Expert Opin Pharmacother 12, no. 1 (January 2011): 85–98. https://doi.org/10.1517/14656566.2010.513701.
Wang, Jenny T., et al. “Management of depression in patients with coronary heart disease: association, mechanisms, and treatment implications for depressed cardiac patients.Expert Opin Pharmacother, vol. 12, no. 1, Jan. 2011, pp. 85–98. Pubmed, doi:10.1517/14656566.2010.513701.

Published In

Expert Opin Pharmacother

DOI

EISSN

1744-7666

Publication Date

January 2011

Volume

12

Issue

1

Start / End Page

85 / 98

Location

England

Related Subject Headings

  • Risk Factors
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Exercise Therapy
  • Depression
  • Cost of Illness
  • Coronary Disease
  • Antidepressive Agents