Depression and coronary heart disease: association and implications for treatment.


Journal Article (Review)

Growing evidence indicates that depression is an important primary and secondary risk factor for coronary heart disease (CHD). Depression is quite common among patients with CHD: prevalence estimates are 14% or higher, and an additional 20% of patients have subclinical or minor depression. This review summarizes evidence that depression is a risk factor for cardiac events in patients with established CHD, suggests potential mechanisms underlying the relationship between depression and adverse cardiac outcomes, and provides evidence for the efficacy of exercise in improving both depression and clinical outcomes in depressed patients with CHD.

Full Text

Duke Authors

Cited Authors

  • Blumenthal, JA

Published Date

  • March 2008

Published In

Volume / Issue

  • 75 Suppl 2 /

Start / End Page

  • S48 - S53

PubMed ID

  • 18540147

Pubmed Central ID

  • 18540147

International Standard Serial Number (ISSN)

  • 0891-1150

Digital Object Identifier (DOI)

  • 10.3949/ccjm.75.suppl_2.s48


  • eng

Conference Location

  • United States