Health-related quality of life in sickle cell disease: past, present, and future.

Journal Article (Journal Article;Review)

Health-related quality of life (HRQL) is defined as the patient's appraisal of how his/her well being and level of functioning, compared to the perceived ideal, are affected by individual health. The study of HRQL in children and adults with sickle cell disease (SCD) has begun to flourish. Given the devastating complications of the disease and other co-morbid factors patients experience that influence HRQL, it is increasingly important to understand HRQL. The focus of this critical review was to examine past and current research in HRQL in SCD where a validated instrument was used. In addition, future directions for HRQL in SCD are explored.

Full Text

Duke Authors

Cited Authors

  • Panepinto, JA; Bonner, M

Published Date

  • August 2012

Published In

Volume / Issue

  • 59 / 2

Start / End Page

  • 377 - 385

PubMed ID

  • 22522407

Pubmed Central ID

  • 22522407

Electronic International Standard Serial Number (EISSN)

  • 1545-5017

Digital Object Identifier (DOI)

  • 10.1002/pbc.24176


  • eng

Conference Location

  • United States