A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.
Journal Article (Journal Article)
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk for suicidality, depression, and functional impairment. We thus conducted a small (N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group. Paroxetine may have promise for subthreshold PTSD.
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Duke Authors
- Bradford, Daniel William
- Davidson, Jonathan R.T.
- Kilts, Jason David
- Marx, Christine Elizabeth
- Naylor, Jennifer C.
- Strauman, Timothy J.
- Strauss, Jennifer Leigh
Cited Authors
- Naylor, JC; Dolber, TR; Strauss, JL; Kilts, JD; Strauman, TJ; Bradford, DW; Szabo, ST; Youssef, NA; Connor, KM; Davidson, JRT; Marx, CE
Published Date
- April 30, 2013
Published In
Volume / Issue
- 206 / 2-3
Start / End Page
- 318 - 320
PubMed ID
- 23276723
Pubmed Central ID
- PMC3788578
Electronic International Standard Serial Number (EISSN)
- 1872-7123
Digital Object Identifier (DOI)
- 10.1016/j.psychres.2012.11.008
Language
- eng
Conference Location
- Ireland