Health disparities in risk for cervical insufficiency.

Journal Article (Journal Article)

BACKGROUND: The purpose of the study was to examine racial/ethnic differences in cervical insufficiency risk. METHODS: We used the US 2005 Natality data file. Analysis was limited to singleton births. The prevalence of cervical insufficiency was examined by the maternal characteristic for each racial group. Unconditional logistic regression modeling was used to assess the association between race and cervical insufficiency while controlling for confounders. RESULTS: Cervical insufficiency risk for Black women was more than twice that for their White counterparts [odds ratio (OR) (95% confidence interval (CI)) of 2.45 (2.22-2.71)]. Prior pregnancy termination showed a dose-response relationship with cervical insufficiency. Compared with women with no history of prior pregnancy termination, primiparous women who have had one pregnancy termination had an OR (95% CI) of 2.49 (2.23-2.77). The OR for two, three and four or more terminations were 4.66 (4.07-5.33), 8.07 (6.77-9.61) and 12.36 (10.19-15.00), respectively. Other predictors of cervical insufficiency included previous preterm birth, parity, marital status, renal disease, history of diabetes, polyhydramnios and anemia. CONCLUSIONS: There were significant racial/ethnic disparities with Black women having increased cervical insufficiency risk, independent of other studied factors. Prior pregnancy termination is also a major risk factor for cervical insufficiency. The White/Black disparity is evident in both primiparous and multiparous women.

Full Text

Duke Authors

Cited Authors

  • Anum, EA; Brown, HL; Strauss, JF

Published Date

  • November 2010

Published In

Volume / Issue

  • 25 / 11

Start / End Page

  • 2894 - 2900

PubMed ID

  • 20643692

Pubmed Central ID

  • PMC2955555

Electronic International Standard Serial Number (EISSN)

  • 1460-2350

Digital Object Identifier (DOI)

  • 10.1093/humrep/deq177


  • eng

Conference Location

  • England