Colonizing the heart from the epicardial side.

Published

Journal Article

The clinical use of stem cells, such as bone marrow-derived and, more recently, resident cardiac stem cells, offers great promise for treatment of myocardial infarction and heart failure. The epicardium-derived cells have also attracted attention for their angiogenic paracrine actions and ability to differentiate into cardiomyocytes and vascular cells when activated during cardiac injury. In a recent study, Chong and colleagues have described a distinct population of epicardium-derived mesenchymal stem cells that reside in a perivascular niche of the heart and have a broad multilineage potential. Exploring the therapeutic capacity of these cells will be an exciting future endeavor.

Full Text

Duke Authors

Cited Authors

  • Bursac, N

Published Date

  • April 30, 2012

Published In

Volume / Issue

  • 3 / 2

Start / End Page

  • 15 -

PubMed ID

  • 22546531

Pubmed Central ID

  • 22546531

Electronic International Standard Serial Number (EISSN)

  • 1757-6512

International Standard Serial Number (ISSN)

  • 1757-6512

Digital Object Identifier (DOI)

  • 10.1186/scrt106

Language

  • eng