Colonizing the heart from the epicardial side.
Journal Article (Editorial)
The clinical use of stem cells, such as bone marrow-derived and, more recently, resident cardiac stem cells, offers great promise for treatment of myocardial infarction and heart failure. The epicardium-derived cells have also attracted attention for their angiogenic paracrine actions and ability to differentiate into cardiomyocytes and vascular cells when activated during cardiac injury. In a recent study, Chong and colleagues have described a distinct population of epicardium-derived mesenchymal stem cells that reside in a perivascular niche of the heart and have a broad multilineage potential. Exploring the therapeutic capacity of these cells will be an exciting future endeavor.
Full Text
Duke Authors
Cited Authors
- Bursac, N
Published Date
- April 2012
Published In
Volume / Issue
- 3 / 2
Start / End Page
- 15 -
PubMed ID
- 22546531
Pubmed Central ID
- PMC3392775
Electronic International Standard Serial Number (EISSN)
- 1757-6512
International Standard Serial Number (ISSN)
- 1757-6512
Digital Object Identifier (DOI)
- 10.1186/scrt106
Language
- eng