Necrotizing sialometaplasia: a sheep in wolf's clothing. Healing as a diagnostic test.

Journal Article (Journal Article)

Necrotizing sialometaplasia is a benign self-limited intraoral lesion that is easily confused both clinically and histologically with squamous cell carcinoma. It presents as a painless ulceration, frequently on the hard palate, that histologically shows necrosis, inflammation, squamous metaplasia, and granulation tissue. It is thought to be due to infarction of minor salivary glands and heals spontaneously in six to 12 weeks. A brief period of observation for evidence of healing can be an important diagnostic clue in distinguishing this entity from cancer, thus saving the patient unnecessary surgery or radiation therapy.

Full Text

Duke Authors

Cited Authors

  • Kinney, RB; Burton, CS; Vollmer, RT

Published Date

  • February 1, 1986

Published In

Volume / Issue

  • 122 / 2

Start / End Page

  • 208 - 210

PubMed ID

  • 3947128

International Standard Serial Number (ISSN)

  • 0003-987X


  • eng

Conference Location

  • United States