Renal agenesis after first trimester exposure to chlorambucil.

Journal Article (Journal Article)

One of a set of twins aborted at 20 weeks' gestation had unilateral renal agenesis after exposure to chlorambucil and prednisone since conception. There are no firm clinical data suggesting that second or third trimester exposure to any of the immunosuppressive drugs is toxic to the fetus, and no absolute cause-and-effect relationship is established in this case.

Full Text

Duke Authors

Cited Authors

  • Steege, JF; Caldwell, DS

Published Date

  • October 1, 1980

Published In

Volume / Issue

  • 73 / 10

Start / End Page

  • 1414 - 1415

PubMed ID

  • 7434066

International Standard Serial Number (ISSN)

  • 0038-4348

Digital Object Identifier (DOI)

  • 10.1097/00007611-198010000-00040


  • eng

Conference Location

  • United States